Date of publication: October 15, 2020

Objectives: 

  • To search and summarize available evidence on the clinical efficacy and effectiveness of PCV10 and PCV13 in preventing IPD, pneumonia and AOM, inducing immune response, and lowering pneumococcal nasopharyngeal carriage
  • To determine which PCV  represents good value for money in the Philippines for preventing mortality and morbidity due to IPD, clinical pneumonia, and AOM for children under 1 year
  • To determine the budget implication of immunizing infants with PCV 10 or PCV 13  in the Expanded Program on Immunization (EPI)
  • To identify the ethical, legal, social, and health system implications (ELSHSI) of immunizing infants with either PCV10 or PCV13 to prevent  mortality and morbidity due to IPD, clinical pneumonia, and AOM.

HTA Full Report:  Reassessment of 10- versus 13-valent Pneumococcal Conjugate Vaccines (PCV) in the Philippines

Evidence summary:  PCV ES OSEC Approved